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Submitted: 11 Mar 2025
Revision: 10 May 2025
Accepted: 31 May 2025
ePublished: 08 Jun 2025
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J Ren Endocrinol. 2025;11: e25196.
doi: 10.34172/jre.2025.25196
  Abstract View: 72
  PDF Download: 33

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Obesity, diabetes, and cancer; a triad of interconnected risks and emerging evidence

Hafez Mohammadhassanzadeh 1 ORCID logo, Zeinab Aliyari Serej 2* ORCID logo

1 Tabriz University of Medical Sciences, Tabriz, Iran.
2 Department of Applied Cell Sciences, Faculty of Advanced Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
*Corresponding Author: Zeinab Aliyari Serej, Email: z_aliyari@yahoo.com

Abstract

Obesity has become a major risk factor for different types of cancer, and highlights research emphasizes the impact of inflammation related to obesity in this connection. Chronic low-grade inflammation associated with excess adipose tissue can disrupt metabolic signaling and immune responses, which may facilitate the tumorigenesis.

Citation: Mohammadhassanzadeh H, Aaliyari-Serej Z. Obesity, diabetes, and cancer; a triad of interconnected risks and emerging evidence. J Ren Endocrinol. 2025;11:e25196. doi: 10.34172/jre.2025.25196.
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