Nickan Research Institute Journal of Renal Endocrinology 2423-6438 7 1 2021 01 01 Renal complications of sickle cell disease e20 e20 10.34172/jre.2021.20 EN Sara Bahadoram https://orcid.org/0000-0001-9531-8270 Bijan Keikhaei https://orcid.org/0000-0002-3087-7650 Mohammad Bahadoram https://orcid.org/0000-0002-7106-9799 Mohammad-Reza Mahmoudian-Sani https://orcid.org/0000-0002-1096-5661 Shakiba Hassanzadeh https://orcid.org/0000-0002-5091-5191 Journal Article 10.34172/jre.2021.20 2021 08 23 2021 10 02 The nephropathy and renal complications of sickle cell disease are associated with various events such as hypoxic or ischemic conditions and reperfusion injury. Erythrocyte sickling occurs following these events and renal medullary acidosis.