Nickan Research Institute Journal of Renal Endocrinology 2423-6438 9 1 2023 01 01 Do antibacterial or antiviral filters protect operating room staff by preventing COVID-19 virus spread from cardiopulmonary bypass machine during open hear surgeries? A case report e20062 e20062 10.34172/jre.2023.20062 EN Manouchehr Hekmat https://orcid.org/0000-0002-5767-0932 Hamid Ghaderi https://orcid.org/0000-0003-0905-2440 Zahra Ansari Aval https://orcid.org/0000-0002-6044-8259 Seyedeh Adeleh Mirjafari https://orcid.org/0000-0003-2780-6736 Mandana Hekmat https://orcid.org/0000-0003-3600-6722 Roshanak Tirdad https://orcid.org/0000-0002-9764-2303 Journal Article 10.34172/jre.2023.20062 2022 09 02 2022 11 14 Open heart surgeries are inevitable during pandemic and there is the possibility of corona virus transmission through oxygenated exhaust during cardiopulmonary bypass (CBP). In this study, researchers try to test the hypothesis by placing an antiviral and antibacterial filter in the air outlet of the oxygenator in order to prevent spread of COVID-19 virus in operating room. The COVID-19 positive patient needed emergency open-heart surgery due to her critical situation. The patient was under cardiopulmonary bypass for almost two hours. Antibacterial and antiviral filters were placed in oxygenator outlet. At the end of the procedure, polymerase chain reaction (PCR) swab was taken from both sides of the filter. The result of the test behind the filter was positive, but at the other side of the filter was negative. This may suggest, the exhaust air from the oxygenator can spread viruses into the room and the antibacterial and antiviral filters may be able to prevent operating room contamination. The installation of filter in the oxygenator exhaust can prevent the spread of COVID-19 viruses into the operating room air. Using this cheap and affordable method, operating room staff safety can be assured.