﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Nickan Research Institute</PublisherName>
      <JournalTitle>Journal of Renal Endocrinology</JournalTitle>
      <Issn>2423-6438</Issn>
      <Volume>9</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2023</Year>
        <Month>01</Month>
        <DAY>01</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>COVID-19 patients’ lung involvement severity as a predictor of kidney dysfunction and coagulopathy disorders</ArticleTitle>
    <FirstPage>e25096</FirstPage>
    <LastPage>e25096</LastPage>
    <ELocationID EIdType="doi">10.34172/jre.2023.25096</ELocationID>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Farinaz</FirstName>
        <LastName>Fattahi</LastName>
      </Author>
      <Author>
        <FirstName>Mohammad Reza</FirstName>
        <LastName>Farnia</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-4397-8661</Identifier>
      </Author>
      <Author>
        <FirstName>Bareza</FirstName>
        <LastName>Rezaei</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-7210-4162</Identifier>
      </Author>
      <Author>
        <FirstName>Hooman</FirstName>
        <LastName>Rafiei</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-8598-9836</Identifier>
      </Author>
      <Author>
        <FirstName>Aisan</FirstName>
        <LastName>Ghasemi Oskui</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-0201-7629</Identifier>
      </Author>
      <Author>
        <FirstName>Amir Mohammad</FirstName>
        <LastName>Amiri</LastName>
        <Identifier Source="ORCID">https://orcid.org/0009-0001-2767-9362</Identifier>
      </Author>
      <Author>
        <FirstName>Mohammad Reza</FirstName>
        <LastName>Rezaei</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-5166-9711</Identifier>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">10.34172/jre.2023.25096</ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2023</Year>
        <Month>03</Month>
        <Day>23</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2023</Year>
        <Month>06</Month>
        <Day>13</Day>
      </PubDate>
    </History>
    <Abstract>Introduction: Kidney dysfunction, coagulopathy disorders, and lung involvement are the most common disorders caused by the COVID-19 virus. Objectives: This study aimed to investigate the correlation of lung involvement severity with kidney dysfunction and coagulopathy disorders in COVID-19 patients. Patients and Methods: This descriptive-analytical study was conducted on 97 patients with COVID-19 referred to Imam Reza hospital in Kermanshah from December 2020 to June 2021. Lung involvement severity, kidney function tests, and coagulation laboratory data were collected. Logistic regression test was conducted to explore the correlation between lung involvement with kidney dysfunction and coagulopathy disorders.  Results: Out of 97 patients, 53 (54.6%) were male, with a mean age of 59.31 ± 16.44 years. The correlation between lung involvement severity with kidney function tests, including, blood urea nitrogen, serum creatinine, and coagulation factors, including prothrombin time (PT), partial thromboplastin time (PTT), and D-dimer, were significant (P &gt; 0.05). Lung involvement severity significantly predicted kidney dysfunction and coagulopathy disorders. Conclusion: Lung involvement severity would be able to predict kidney dysfunction and coagulopathy disorders in patients with COVID-19.</Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">Lung involvement</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">COVID-19</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Kidney dysfunction</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">D-dimer</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Coagulopathy</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">SARS-CoV-2</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>