Nickan Research Institute Journal of Renal Endocrinology 2423-6438 10 1 2024 01 01 Assessing predictors of pulmonary sequel in COVID-19 patients through lung CT imaging; a two-month comprehensive evaluation e25180 e25180 10.34172/jre.2024.25180 EN Amir Behnam Kharazmi https://orcid.org/0000-0003-1192-4893 Zeinab Khazaei Poul https://orcid.org/0009-0005-9518-0749 Seyed Hamidreza Mirbehbahani https://orcid.org/0000-0002-6126-462X Alireza Kashefizadeh https://orcid.org/0000-0001-7997-0365 Tahereh Sabaghian https://orcid.org/0000-0001-7689-8150 Journal Article 10.34172/jre.2024.25180 2024 10 09 2024 12 21 Introduction: The emergence of COVID-19 has resulted in an unprecedented global health crisis. While acute respiratory symptoms are well-documented, there is growing concern regarding the long-term pulmonary effects in survivors. Objectives: This study aimed to evaluate the pulmonary sequel of COVID-19 patients referred to Imam Hossein Hospital, Tehran, Iran, in 2022. Patients and Methods: This longitudinal study involved 180 patients who recovered from COVID-19 at Imam Hossein Hospital in 2022, selected based on confirmed diagnoses and resolution of acute symptoms. Data were collected through a demographic questionnaire and a clinical checklist. Participants were followed for two months, during which lung involvement was categorized as clear or non-clear, allowing for the evaluation of associations between demographic and clinical data with computed tomography (CT) outcomes. Results: Results indicated a statistically significant correlation between clinical findings, including lung involvement exceeding 30%, intensive care unit (ICU) admission necessity, intubation status, and prolonged hospitalization duration in patients with clear or non-clear pulmonary status. Lung involvement greater than 30% and longer hospitalization duration were identified as independent predictors of adverse pulmonary outcomes, with odds ratios of 2.30 and 2.47, respectively. Conclusion: The study highlights a significant relationship between clinical findings and pulmonary outcomes in COVID-19 patients, particularly emphasizing that lung involvement exceeding 30% and prolonged hospitalization are critical independent predictors of adverse respiratory complications.